Dr. Ashaq Hussain
Covid-19 pandemic has impacted almost every corner of life, causing global economies to stall, changing the way we work and interact with our loved ones, and stretching healthcare systems to the limit.COVID-19 vaccination is now offering a way to transition out of this phase of the pandemic.Fortunately, the beginning of 2021 saw numerous vaccines given emergency approval and begin their roll out in countries across the world. All WHO-approved vaccines have been shown to be highly effective at protecting you against severe illness from COVID-19. The best vaccine to get is the one most readily available to you!
Covishield has been co-produced by Oxford University and AstraZeneca and is being produced in India by the Serum Institute of India, Pune. It is a one-of-a-kind deal in which half the price per vaccine goes to Oxford. Kovishield is one of the most popular vaccines in the world as many countries are using it. Kovishield is the most effective against mutant strains (ie mutated viruses). CoveShield is a viral vector type vaccine. It is made through a single virus that is derived fromh an adenovirus (a virus found in the feces of chimpanzee) found in chimpanzees.This is the same virus that causes cold in chimpanzee, but the genetic structure of this virus combines with the virus of COVID, so using the adeno-virus induces the vaccine immunity system to make antibodies in the body. Coveshield is also approved by WHO. Its effectiveness rate is 70 percent. This vaccine protects against severe symptoms of corona and the infected person recovers quickly. It also prevents the person from going on ventilator. It is very easy to maintain because it can be carried anywhere from about 2 ° to 8 ° C, so the remaining vaccine vials can be stored in the refrigerator after its use.
Covaxin is another vaccine co-produced by ICMR and Bharat Biotech. It has been built on the oldest of vaccine making ie traditional inactivated platform, Inactivated means that the dead virus is injected into the body, which produces antibodies and then the same antibody kills the virus. This vaccine is not able to infect people because making a vaccine is of very fine balance so that the virus is not activated in the body. This activated virus prepares the body's immune system to recognize the real virus and fights it when an infection occurs and tries to eradicate it. This vaccine threatens the corona virus, not humans. Covaxine has an effective 78%. A research has also reported that this vaccine can reduce the risk of fatal infection and mortality by 100 percent. Recent research has claimed that covaxin is effective against all variants of the Corona.
The third common Sputnik-V vaccince has been developed by the Gamalaya Research Institute of Moscow, which will be built by Dr. Reddy's Lab in India. It can also be stored at 2-8 ° C. Sputnik V is also a viral vector vaccine, but one major difference between it and the rest of the vaccine is that the rest of the vaccine is made from one virus, whereas it has two. These two different types of viruses arevAdenovirus-26 (Ad26) and Adenovirus-5 (Ad5) causing colds, colds and other respiratory diseases. It mimics the prickly proteins found in the corona virus (Spike protein - the same protein that helps in entry into the cells of the body, ie cells), which attacks the body first. Immune system is activated as soon as the vaccine reaches the body. And antibodies are produced in the body. These antibodies protect the body from the corona virus.
Apart from these three, there are 2 more vaccines in the world which have been given emergency approval but are not currently valid in India, which are of Modarna and Pfizer,vWhile Modarna has to store at -20 °C, on the other hand Pfizer's vaccine has to be protected from -70 °C to -75 °C which is why India is lagging behind in approving these vaccines. It is difficult to develop such a system in which to maintain this temperature in India. Apart from this, one thing is different from the conventional technique that has been used in making this vaccine.
It may be noted that Comparative studies are for your information only because so far only three vaccines are approved in India (Covishield, Kovaxin and Sputnik) to protect you from getting serious and preventing ventilator visit. So whatever vaccine you come across, get it vaccinated immediately. Because the vaccine of all three avoids the risk of getting serious and protects you. Safe and effective vaccines are a game-changing tool: but for the foreseeable future we must continue wearing masks, cleaning our hands, ensuring good ventilation indoors, physically distancing and avoiding crowds.
(Dr. Ashaq Hussain is Assistant Professor Chemistry (Selection Grade) at Govt. Degree College Chatroo Jammu and Kashmir and can be reached at [email protected])